| CatalogCode: | NLS8044 |
| ProductName: | Nuclear Receptor Rev-ErbA Alpha Antibody |
| Product Description: | Rabbit Polyclonal anti-Nuclear Receptor Rev-ErbA Alpha |
| Clonality: | Polyclonal |
| Immunogen: | internal domain of human |
| CrossReactivity: | Human |
| Packaging: | 0.05 ml |
| Uses: | Immunohistochemistry of Formalin fixed paraffin embedded sections. Suggested starting dilution is |
| Background: | Rev-erbA alpha, a NR1 Thyroid Hormone-Like Receptor, is encoded by the same genomic locus as, but transcribed from the opposite strand of, Thyroid Hormone Receptor Alpha (TR Alpha). Rev-erbA alpha is a target of Nuclear Receptor ROR Alpha (Delerive et al. 2002), and a transcription regulator that has been shown to affect myocyte differentiation, adipogenesis, and lipoprotein metabolism. Recently Reb-erbA alpha has been shown to affect circadian rhythms by regulating cyclic Bmal1 transcription (Preitner et al. 2002, Ueda et al. 2002). Mice lacking Rev-erbA alpha show abnormal postnatal cerebellar development. Rev-erbA alpha expression has been documented in human skeletal muscle and a variety of mouse and rat tissues. ESTs have been isolated from human tissue libraries, including cancerous adrenal, blood, brain, breast, colon, duodenum, fetus, head/neck, kidney, lung, skeletal muscle, skin, synovium, and uterus, and normal brain, breast, colon, eye, heart, pancreas, pituitary, rostate, skeletal muscle, skin, testis, and thyroid. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Peptide affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide |
| ListPrice: | 325 |
| AppSummary: | IHC-P |
| SpeciesSummary: | Hu |
| ProteinTarget: | Nuclear Receptor Rev-ErbA Alpha (NR1D1) |
| PackageSize: | 0.05 ml |
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