| CatalogCode: | NLS7979 |
| ProductName: | CDC7-Related Protein Kinase Antibody |
| Product Description: | Rabbit Polyclonal anti-CDC7-Related Protein Kinase |
| Clonality: | Polyclonal |
| Immunogen: | Kinase domain of human |
| CrossReactivity: | Human |
| Packaging: | 0.05 ml |
| Uses: | Immunohistochemistry of Formalin fixed paraffin embedded sections. Suggested starting dilution is |
| Background: | CDC7L1, CDC7 type protein kinase, regulates firing of the origins of initiation in DNA replication. CDC7L1 forms a complex with a Dbf4-related regulatory subunit to generate an active kinase. Mini-chromosome maintenance protein (MCM) is the major physiological target of Cdc7L1. At least three mRNA variants have been reported. Overexpression of the CDC7L1 protein may be associated with neoplastic transformation for some tumors. CDC7L1 has been documented in a wide range of tissues. One variant is expressed ubiquitously in human tissues while at least one other has been shown to be testis-specific. ESTs have been isolated from several tissue libraries, including normal embryo, gallbladder, lymph node and thymus and cancerous duodenum and embryo. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Peptide affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide |
| ListPrice: | 325 |
| AppSummary: | IHC-P |
| SpeciesSummary: | Hu |
| ProteinTarget: | CDC7-Related Protein Kinase (CDC7L1) |
| PackageSize: | 0.05 ml |
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