| CatalogCode: | NLS7967 |
| ProductName: | NIMA (Never In Mitosis Gene A)-Related Kinase 9 Antibody |
| Product Description: | Rabbit Polyclonal anti-NIMA (Never In Mitosis Gene A)-Related Kinase 9 |
| Clonality: | Polyclonal |
| Immunogen: | Pro/Ser/Thr rich domain of human |
| CrossReactivity: | Human |
| Packaging: | 0.05 ml protein A purified Rabbit antisera. |
| Uses: | Immunohistochemistry of Formalin fixed paraffin embedded sections. |
| Localization: | Cytoplasmic |
| Background: | NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | protein A purified |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline, pH 7.7 |
| ListPrice: | 325 |
| AppSummary: | IHC-P |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-DKFZp434D0935 antibody; Anti-KIAA1995 antibody; Anti-MGC138306 antibody; Anti-MGC16714 antibody; Anti-Nek 8 antibody; Anti-NEK 9 antibody; Anti-Nek8 antibody; Anti-NERCC 1 antibody; Anti-Nercc 1 kinase antibody; Anti-NERCC antibody; Anti-NERCC1 antibody; Anti-Nercc1 kinase antibody; Anti-Never in mitosis A related kinase 9 antibody; Anti-NIMA related kinase 8 antibody; Anti-NIMA related kinase Nek 8 antibody; Anti-NIMA related kinase Nek 9 antibody; Anti-NIMA related kinase Nek8 antibody; Anti-NIMA related kinase Nek9 antibody; Anti-NimA related protein kinase 9 antibody; Anti-Serine/threonine protein kinase Nek 9 antibody; Anti-Serine/threonine protein kinase Nek9 antibody |
| ProteinTarget: | NIMA (Never In Mitosis Gene A)-Related Kinase 9 (NEK9) |
| PackageSize: | 0.05 ml |