| CatalogCode: | NLS698 |
| ProductName: | Adrenergic Alpha 1B Antibody |
| Product Description: | Rabbit Polyclonal anti-Adrenergic Alpha 1B |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide [KLH conjugated] made to the C-term |
| CrossReactivity: | Human. There is 75 % rat identity and 85 % rat homology. There is 85 % mouse identity and 90 % mouse homology. |
| Packaging: | 0.05 ml of affinity purified sera in phosphate buffered saline, PH 7.7 containing 0.01% sodium azide. |
| Uses: | Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. The recommended dilution is: 3 ug/ml to 16 ug/ml. |
| Background: | The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Peptide affinity purified |
| Host_Name: | Rabbit |
| ListPrice: | 375 |
| AppSummary: | IHC-Fr, IHC-P |
| SpeciesSummary: | Hu |
| ProteinTarget: | Adrenergic Alpha 1B |
| PackageSize: | 0.05 ml |
| NotesMain: | Genbank accession number: NM_000679 |