| CatalogCode: | NLS5651 |
| ProductName: | Nuclear Receptor COUP-TFII Antibody |
| Product Description: | Rabbit Polyclonal anti-Nuclear Receptor COUP-TFII |
| Clonality: | Polyclonal |
| Immunogen: | N-terminal to DNA binding domain of human |
| CrossReactivity: | Human |
| Packaging: | 0.05 ml |
| Uses: | Immunohistochemistry of Formalin fixed paraffin embedded sections. Suggested starting dilution is |
| Background: | COUP-TFII, a NR2 Hepatocyte NF4-Like receptor, has been shown to affect neuronal development and differentiation, homeostasis in various human tissues, mesenchymal-epithelial interactions during organogenesis, and the development of the cardiovascular system. COUP-TFII interacts with and modulates several nuclear receptors, including estrogen receptor alpha (ER alpha), thyroid hormone receptors (TR), PPAR alpha, and retinoic acid receptors (RAR). Mice lacking COUP-TFII show abnormal heart and vascular development. COUP-TFII expression has been documented in human adrenal, lung, kidney, liver, spleen, skeletal muscle, and breast. ESTs have been isolated from human tissue libraries, including cancerous adrenal, bladder, brain, breast, colon, head/neck, kidney, lung, ovary, pancreas, pituitary, prostate, skeletal muscle, skin, smooth muscle, stomach, synovium, and uterus, and normal brain, adipose, adrenal, blood, brain, breast, cervix, ear, embryo, gallbladder, ganglion, heart, kidney, liver/spleen, lung, ovary, placenta, prostate, skin, spleen, testis, uterus, and vessel. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Peptide affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide |
| ListPrice: | 375 |
| AppSummary: | IHC-P |
| SpeciesSummary: | Hu |
| ProteinTarget: | Nuclear Receptor COUP-TFII (NR2F2) |
| PackageSize: | 0.05 ml |
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