| CatalogCode: | | NLS475 |
| ProductName: | | Histamine H3 Receptor Antibody |
| Product Description: | | Rabbit Polyclonal anti-Histamine H3 Receptor |
| Clonality: | | Polyclonal |
| Immunogen: | | Synthetic peptide [KLH conjugated] made to the 3rd cytoplasmic loop. |
| CrossReactivity: | | Human. There is 22% identity and 28% homology in mouse. There is 22% identity and 28% homology in rat. |
| Packaging: | | 0.05 ml of affinity purified sera in Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide. |
| Uses: | | Immunohistochemistry with formalin fixed paraffin embedded tissues. Western Blot. Not tested for other uses. The recommended dilution is: 2 ug/ml to 8 ug/ml. |
| Background: | | H3 Histamine Receptor regulates the release of the neurotransmitters norepinephrine and somatostatin. In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons in both the central and peripheral nervous systems, it acts as a presynaptic heteroreceptor. Multiple isoforms of H3 receptors are produced by alternative splicing. Histamine H3 receptor has been reported primarily in brain. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | Peptide affinity purified |
| Host_Name: | | Rabbit |
| ListPrice: | | 375 |
| AppSummary: | | IHC-Fr, IHC-P, WB |
| SpeciesSummary: | | Hu |
| ProteinTarget: | | Histamine H3 Receptor |
| PackageSize: | | 0.05 ml |
| NotesMain: | | Genbank accession number: NM_007232 |
| more information: | | company product webpage |