| CatalogCode: | NLS463 |
| ProductName: | Neuropeptide FF 2 Receptor Antibody |
| Product Description: | Rabbit Polyclonal anti-Neuropeptide FF 2 Receptor |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide [KLH conjugated] made to the N-term extracellular |
| CrossReactivity: | Human. There is 45/55% identity/homology with mouse and 30/45% identity/homology with rat. |
| Packaging: | 0.05 ml of affinity purified sera in Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide. |
| Uses: | Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. The recommended dilution is: 2.5 ug/ml to 20 ug/ml. |
| Background: | The Neuropeptide FF 2 Receptor (NPFF2/HLWAR77/NPGPR) is a Neuropeptide Receptor GPCR. This receptor has high affinity for NPAF and NPFF, and is also weakly activated by FMRF-amide (Phe-Met-Arg-Phe-amide) and a variety of related peptides. The receptor is expressed in brain regions associated with opiate activity, consistent with the pain-modulating activity of these peptides, and in adipose tissue, suggesting other physiological and pathophysiological activities for FMRF-amide neuropeptides (Elshourbagy et al, 2000). Two isoforms are produced by alternative splicing. NPFF2 receptor has been reported to be expressed in various tissues, including brain, heart, intestine, placenta, prostate, spleen, adipose, spinal cord, colon, kidney, liver, lung, ovary, testis, pancreas, and thymus. ESTs have been isolated from fetal and placenta libraries. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Peptide affinity purified |
| Host_Name: | Rabbit |
| ListPrice: | 375 |
| AppSummary: | IHC-Fr, IHC-P |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Neuropeptide FF2 antibody, anti-NPFF2 antibody, anti-G protein-coupled receptor 74 antibody, anti-GPR74 antibody, anti-HLWAR77 antibody, anti-NPFF2 antibody, anti-NPFF2 receptor antibody |
| ProteinTarget: | Neuropeptide FF 2 Receptor |
| PackageSize: | 0.05 ml |
| NotesMain: | Genbank accession number: NM_004885 |
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