| CatalogCode: | | NLS4577 |
| ProductName: | | Frizzled-4 Antibody |
| Product Description: | | Rabbit Polyclonal anti-Frizzled-4 |
| Clonality: | | Polyclonal |
| Immunogen: | | N-terminal extracellular domain of human |
| CrossReactivity: | | Human |
| Packaging: | | 0.05 ml Rabbit antisera. |
| Uses: | | Immunohistochemistry of Formalin fixed paraffin embedded sections. |
| Localization: | | Cell Membrane |
| Background: | | FZD4 is a Frizzled Receptor involved in mediating Wnt signaling. A splicing variant of frizzled-4, FZD4s, encodes a soluble-type positive regulator of the Wnt signaling pathway. Mutations in FZD4 are associated with retinal angiogenesis. FZD4 is widely expressed, particularly in heart, skeletal muscle, ovary, and fetal kidney. Transcripts have also been identified in liver, kidney, pancreas, spleen, and fetal lung, and in smaller amounts in placenta, adult lung, prostate, testis, colon, and fetal brain. FZD4 expression has not been reported in several cancer cell lines studied. ESTs have been isolated from adipose, adrenal, B-cell/lung/testis, bone marrow, brain, breast, colon, embryo, gallbladder, head/neck, heart, heart/melanocyte/uterus, kidney, liver, liver/spleen, lung, placenta, prostate, skeletal muscle, skin, and vessel libraries. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host_Name: | | Rabbit |
| Buffer: | | Phosphate buffered saline, pH 7.7 |
| ListPrice: | | 375 |
| AppSummary: | | IHC-P |
| SpeciesSummary: | | Hu |
| ALTnames: | | Anti-CD 344 antibody; Anti-CD 344 antigen antibody; Anti-CD344 antibody; Anti-EVR1 antibody; Anti-Fz-4 antibody; Anti-FZD4 antibody; Anti-FZD4S antibody; Anti-FzE4 antibody; Anti-GPCR antibody; Anti-WNT receptor frizzled-4 antibody |
| ProteinTarget: | | Frizzled-4 (FZD4) |
| PackageSize: | | 0.05 ml |
| more information: | | company product webpage |
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