| CatalogCode: | | NLS2652 |
| ProductName: | | Leukocyte Antigen CD97 Antibody |
| Product Description: | | Rabbit Polyclonal anti-Leukocyte Antigen CD97 |
| Clonality: | | Polyclonal |
| Immunogen: | | Synthetic peptide [KLH conjugated] made to the 3rd cytoplasmic loop |
| CrossReactivity: | | Human. There is 87% identity and 100% homology in mouse. |
| Packaging: | | 0.05 ml of affinity purified sera in Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide. |
| Uses: | | Immunohistochemistry with formalin fixed paraffin embedded tissues. Immunocytochemistry. Not tested for other uses. The recommended dilution is: 5 ug/ml to 8 ug/ml. |
| Background: | | CD97, a CD55 Receptor, is a leukocyte antigen located on most activated leukocytes. CD97 is highly homologous to EMR2 with five EGF-like domains in the N-terminal extracellular domain, suggesting that it may be involved in cell signaling as well as in cell adhesion (Hamann et al., 1996). Two variants are produced by alternative splicing, where the shorter form lacks exons 5 and 6 and reduces the number of EGF-like domains from 5 to 3, compared to the full-length isoform. CD97 is associated with with the activated lesions of multiple sclerosis. CD97 expression is also implicated in the dedifferentiation of colon and thyroid tumors. CD97 is expressed abundantly in cells of hematopoietic origin and is markedly upregulated on activated T and B cells. ESTs have been isolated from a wide variety of tissue libraries. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | Peptide affinity purified |
| Host_Name: | | Rabbit |
| ListPrice: | | 325 |
| AppSummary: | | IHC-Fr, IHC-P, ICC |
| SpeciesSummary: | | Hu |
| ProteinTarget: | | Leukocyte Antigen CD97 |
| PackageSize: | | 0.05 ml |
| NotesMain: | | Genbank accession number: U76764 |
| more information: | | company product webpage |