| CatalogCode: | NLS1544 |
| ProductName: | P2Y12 Platelet ADP Receptor Antibody |
| Product Description: | Rabbit Polyclonal anti-P2Y12 Platelet ADP Receptor |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide [KLH conjugated] made to the 3rd cytoplasmic loop |
| CrossReactivity: | Human. There is 78 % rat identity and 83 % rat homology. There is 83 % mouse identity and 89 % mouse homology. |
| Packaging: | Immunogen affinity purified Rabbit antisera. |
| Uses: | Immunohistochemistry with formalin fixed paraffin embedded tissues. |
| Localization: | Cell Membrane |
| Background: | P2Y12 is a Purinergic Receptor essential for the aggregation of blood platelets. There is evidence that mutations in P2Y12 cause a bleeding disorder, suggesting that knowledge of the P2Y12 receptor could advance the development of antiplatelet agents to treat cardiovascular diseases. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries. Cognate |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Host_Name: | Rabbit |
| Buffer: | PBS |
| ListPrice: | 375 |
| AppSummary: | ICC, IHC-P |
| SpeciesSummary: | Hu |
| ALTnames: | anti-ADP-glucose receptor antibody; anti-HORK3 antibody; anti-P2Y12 antibody; anti-Platelet ADP receptor antibody; anti-SP1999 antibody |
| ProteinTarget: | P2Y12 Platelet ADP Receptor |
| NotesMain: | Genbank accession number: NM_022788 |
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