| CatalogCode: | NLS1495 |
| ProductName: | Leukotriene B4 Receptor BLT1 Antibody |
| Product Description: | Rabbit Polyclonal anti-Leukotriene B4 Receptor BLT1 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide [KLH conjugated] made to the C-term |
| CrossReactivity: | Human, Rat. There is 87% identity and 93% homology with mouse. |
| Packaging: | 0.05 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | Immunohistochemistry with formalin fixed paraffin embedded tissues. |
| Localization: | Integral membrane protein. |
| Background: | BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes (Yokomizo et al., 1997). Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor (Yokomizo et al., 1997). Part of the coding regions of BLTR2 (LS57180) have been duplicated and are part of the 5' UTR noncoding regions of the clusters BLT1 (LS190955) and CIDE-B (LS54843) on chromosome 14. BLT1 has been reported in blood, bone marrow, brain, heart, liver, and skeletal muscle. In addition, BLT1 has been shown to be highly expressed in leukocytes and lymphoid tissues such as spleen, thymus, and lymph node. ESTs have been isolated from B-cell/lung/testis, breast, colon, eye, kidney, skin, spleen, testis, and tonsil libraries. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Host_Name: | Rabbit |
| Buffer: | PBS |
| ListPrice: | 375 |
| AppSummary: | IHC-P |
| SpeciesSummary: | Hu, Rt |
| ALTnames: | anti-BLT antibody; anti-BLT1 antibody; anti-BLTR antibody; anti-Chemokine receptor like 1 antibody; anti-CMKRL1 antibody; anti-G protein coupled receptor 16 antibody; anti-GPR16 antibody; anti-Leukotriene B4 G Protein coupled receptor antibody; anti-Leukotriene B4 receptor 1 antibody; anti-LTB4R antibody; anti-LTBR1 antibody; anti-P2RY7 antibody; anti-P2Y7 antibody; anti-Purinergic receptor P2Y G protein coupled 7 antibody |
| ProteinTarget: | Leukotriene B4 Receptor BLT1 |
| PackageSize: | 0.05 ml |
| NotesMain: | Genbank accession number: D89079 |