| CatalogCode: | | NLS1486 |
| ProductName: | | G Protein-Coupled Receptor GPR105 Antibody |
| Product Description: | | Rabbit Polyclonal anti-G Protein-Coupled Receptor GPR105 |
| Clonality: | | Polyclonal |
| Immunogen: | | Synthetic peptide [KLH conjugated] made to the C-term |
| CrossReactivity: | | Human. The immunogen used for this antibody has 80/60% homology/identity with the mouse protein. There appears to be no overlap of the immunogen and the rat sequence. |
| Packaging: | | 0.05 ml peptide affinity purified Rabbit antisera. |
| Uses: | | Immunohistochemistry with formalin fixed paraffin embedded tissues. Immunocytochemistry. Western Blot. Not tested for other uses. The recommended dilution is: 3 ug/ml to 22 ug/ml. |
| Background: | | GPR105 is a Sugar-Sensing Receptor. GPR105 is a G-protein-coupled receptor identifying a quiescent, primitive population of hematopoietic cells restricted to bone marrow. GPC105 has been suggested to mediates primitive cell responses to specific hematopoietic microenvironments and extends the known immune system functions of P2Y receptors to the stem cell level. GPR105 has also been suggested to play an important role in peripheral and neuroimmune function in response to extracellular UDP-sugars. GPR105 has been reported to be expressed in brain. ESTs have been isolated from kidney, placenta, uterus, and heart/melanocyte/uterus libraries. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | peptide affinity purified |
| Host_Name: | | Rabbit |
| ListPrice: | | 375 |
| AppSummary: | | IHC-Fr, IHC-P, ICC, WB |
| SpeciesSummary: | | Hu |
| ProteinTarget: | | G Protein-Coupled Receptor GPR105 |
| PackageSize: | | 0.05 ml |
| NotesMain: | | Genbank accession number: NM_014879 |
| more information: | | company product webpage |