| CatalogCode: | | NLS1167 |
| ProductName: | | Histamine H1 Receptor Antibody |
| Product Description: | | Rabbit Polyclonal anti-Histamine H1 Receptor |
| Clonality: | | Polyclonal |
| Immunogen: | | Synthetic peptide [KLH conjugated] made to the 2nd extracellular loop |
| CrossReactivity: | | Human. There is 53 % rat identity and 59 % rat homology. There is 53 % mouse identity and 59 % mouse homology. |
| Packaging: | | 0.05 ml Rabbit antisera. |
| Uses: | | Optimal dilutions should be determined by the end user. |
| Localization: | | Cell membrane; Multi-pass membrane protein |
| Background: | | The H1 Histamine Receptor has been implicated in the inflammatory cascade and allergic response. It is expressed by some inflammatory cells and by vascular smooth muscle as well as smooth muscle of other organs. Activation of this receptor expressed in the central nervous system has been shown to regulate the release of neurotransmitters and hormones. H1 receptors modulate a variety of physiological functions including arousal, anxiety, nociception, learning, and food and water intake. The histamine H1 receptor has been reported to be expressed in brain, kidney, lung, nasal cavity, placenta, skeletal and smooth muscle, synovium, and vessel. ESTs have been isolated from B-cell/lung/testis, brain, heart, liver/spleen, lung, and nerve libraries. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host_Name: | | Rabbit |
| Buffer: | | PBS [pH7.7] |
| ListPrice: | | 375 |
| AppSummary: | | IHC |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-H1R antibody; anti-HisH1 antibody; anti-Histamine H1 receptor antibody; anti-Histamine receptor H1 antibody; anti-Histamine receptor subclass H1 antibody |
| ProteinTarget: | | Histamine H1 Receptor |
| PackageSize: | | 0.05 ml |
| more information: | | company product webpage |