| Catalog Code: | NB600-820 |
| Product Type: | Primary Antibody |
| Product Name: | PDK1 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 5163 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-PDK1 |
| Cross Reactivity: | Expected cross-reactivity: Human. Mouse, Rat, Dog |
| Species Summary: | Hu |
| Background: | Gene ID: 5163 |
| Alternate Names: | anti-PDK1 antibody, anti-pyruvate dehydrogenase kinase antibody, anti-isoenzyme 1antibody, anti-HGNC:8809 antibody, anti-mitochondrial pyruvate dehydrogenase kinase isoenzyme 1 antibody, anti-pyruvate dehydrogenase kinase antibody, anti-isoenzyme 1 antibo |
| Immunogen: | Synthetic peptide: C-DFKDKSAEDAK, representing the internal regionof the human protein according to NP_002601.1 |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline containing 0.02% Na azide (pH7.3) with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 65-70kDa band observed in Human Liver lysates (calculated MW of 49.2kDa according to NP_002601.1). The observed molecular weight corresponds to earlier findings in literature |
| Application Summary: | ELISA, WB |
| General References: | Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.Science. 2005 Feb 18;307(5712):1098-101. PMID: 15718470 |
| Notes Main: | Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic acti |