| CatalogCode: | NB600-818 |
| ProductName: | STX1A Antibody |
| Product Description: | Goat Polyclonal anti-STX1A |
| Clonality: | Polyclonal |
| Immunogen: | Synethtic peptide: KDRTQELRTAKD-C, representing the N Terminus of the human protein according to NP_004594.1; NP_443106.1; |
| CrossReactivity: | Mouse. Other species have not been tested. Expected cross-reactivity based upon sequence homology: Human, Mouse, Rat, Dog |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:3295,000. Western Blot: Approx 35kDa band observed in Mouse Brain lysates (calculated MW of 33.0kDa according to NP_004594.1 and 33.295kDa according to NP_443106.1). Recommended concentration: 0.01-0.03ug/ml. |
| Control: | Mouse brain lysate |
| Background: | Please note this product is expected to recognize the products of 2 different genes. Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995).[supplied by OMIM] |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline containing 0.02% Na azide (pH7.3) with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Mu |
| ALTnames: | anti-STX1A antibody, anti-syntaxin 1A (brain)antibody, anti-HGNC:11433 antibody, anti-HPC-1 antibody, anti-STX1 antibody, anti-p35-1 antibody, anti-adipocyte antibody, anti-C1Q and collagen domain containing antibody, anti-adiponectin antibody, anti-adipose most abundant gene transcript 1 antibody, anti-syntaxin 1B2 antibody |
| ProteinTarget: | STX1A / STX1B2 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Kang Y, Leung YM, Manning-Fox JE, Xia F, Xie H, Sheu L, Tsushima RG, Light PE, Gaisano HY. Syntaxin-1A inhibits cardiac KATP channels by its actions on nucleotide binding folds 1 and 2 of sulfonylurea receptor 2A.J Biol Chem. 2004 Nov 5;279(45):47125-31. Epub 2004 Aug 31. PMID: 15339904 |
| NotesMain: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application.Gene ID number: 6804; 112755 (human) |
| Gene_Id: | 6804/112755 |