| CatalogCode: | NB600-810 |
| ProductName: | GDF15 Antibody |
| Product Description: | Goat Polyclonal anti-GDF15 |
| Clonality: | Polyclonal |
| Immunogen: | Synethtic peptide: C-QKTDTGVSLQTYDD, representing the C Terminus of the human protein according to NP_004855.1 |
| CrossReactivity: | Human. Other species have not been tested. Expected cross-reactivity based upon sequence homology: Human, Mouse, Rat |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:295,000. Western Blot: Approx 35kDa band observed in Human Prostate lysates (calculated MW of 34.1kDa according to NP_004855.1). Recommended concentration: 0.1-0.3ug/ml. |
| Background: | Bone morphogenetic proteins (e.g., BMP5; MIM 112265) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM] |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline containing 0.02% Na azide (pH7.3) with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-GDF15 antibody, anti-PDF antibody, anti-MIC1 antibody, anti-PLAB antibody, anti-MIC-1 antibody, anti-NAG-1 antibody, anti-PTGFB antibody, anti-GDF-15 antibody, anti-growth differentiation factor 15 antibody, anti-PTGF-beta antibody, anti-prostate differentiation factor antibody, anti-NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 antibody |
| ProteinTarget: | GDF15 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Wollmann W, Goodman ML, Bhat-Nakshatri P, Kishimoto H, Goulet RJ Jr, Meharotra S, Morimiya A, Badve S, Nakshatri H. The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells.Carcinogenesis. 2005 Jan 27; [Epub ahead of print] PMID: 15677629 |
| NotesMain: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application.Gene ID number: 9518 (human) |
| Gene_Id: | 9518 |
| Omim_ID: | NB100-2039 |
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