| Catalog Code: | NB600-755 |
| Product Type: | Primary Antibody |
| Product Name: | Huntingtin Antibody |
| List Price: | 325 |
| Clonality: | Monoclonal |
| Gene ID: | 3064 |
| Host: | Mouse |
| Clone: | HDA3E10 |
| Isotype: | IgG1 |
| Product Description: | Mouse Monoclonal anti-Huntingtin (HDA3E10) |
| Cross Reactivity: | Cross-reacts with Human, Rat and Mouse.Not yet tested in other species. |
| Species Summary: | Hu, Rt, Mu |
| Background: | The combined use of clones ab7666, ab7667 and ab7668 demonstrate that huntingtin is enriched in neuronal cells in the brain. |
| Alternate Names: | anti-HD antibody, anti-HD protein antibody, anti-HDH antibody, anti-HTT antibody, anti-HUNTINGTON CHOREA antibody, anti-Huntington's disease protein homolog antibody, anti-IT15 antibody, anti-ZHD antibody |
| Immunogen: | Recombinant fragment, corresponding to amino acids 997-1276 of Huntingtin. |
| Localization: | Cytoplasmic |
| Specificity: | This antibody reacts with an epitope corresponding to the HDA region (amino acids 1171 - 1177) of the huntingtin protein. |
| Purity: | IgG purified |
| Buffer: | n/a |
| Packaging: | 100 micrograms Preservatives Stabilisers: 0.1% Sodium Azide (NaN3) |
| Package Size: | 0.1 mg |
| Uses: | Immunohistology - frozen (paraffin not tested)Western blotting - detects a 350kD band on western blots but also detects smaller degradation products of huntingtin. This clone recognizes both denatured and native huntingtin in human brain.Immunoprecipitati |
| Application Summary: | IF, IHC-Fr, IP, WB |
| General References: | General / background references:Wilkinson FL et al. Localization of rabbit huntingtin using a new panel of monoclonal antibodies. Brain Res Mol Brain Res 69:10-20 (1999). |
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