| Catalog Code: | NB600-635 |
| Product Type: | Primary Antibody |
| Product Name: | NF-kB Antibody |
| List Price: | 325 |
| Clonality: | Polyclonal |
| Gene ID: | 4790 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-NF-kB |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | p65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory pr |
| Alternate Names: | anti-NFKB 3 antibody, anti-NFKB3 antibody, anti-Nuclear Factor NF Kappa B p65 Subunit antibody, anti-Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells antibody, anti-RELA antibody, anti-Transcription Factor p65 antibody, anti-V Rel Avian |
| Immunogen: | Synthetic peptide (Human) conjugated to KLH. |
| Localization: | Cytoplasmic and Nuclear |
| Specificity: | Recognition is at the N-terminal region of this subunit. This antibody will supershift any NFkB complex containing the human p65 subunit. Control peptide (NB 600-635) will compete only with the specific reaction of antiserum with Human p65 (Rel A). |
| Purity: | Whole antisera |
| Buffer: | Preservative: 0.01% Sodium Azide |
| Packaging: | 100 microlitres Liquid (sterile filtered) |
| Package Size: | 0.1 ml |
| Uses: | This antibody can be used for ELISA, IP, GS, and Western Blot. Not tested in other applications. Recommended Starting Dilution:* ELISA: Use at an assay dependant dilution. GSA: 0.5 - 1.0 ul IP: Use at an assay dependant dilution. WB: 1/1000. Detects a |
| Application Summary: | ELISA, GS, IP, WB |
| General References: | General / background references:Baldwin AS The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 14:649-83 (1996). |
| Product References: | 1. Silver, A. E., Beske, S. D., Christou, D. D., Donato, A. J., Moreau, K. L., Eskurza, I., Gates, P. E., and Seals, D. R. (2007) Overweight and Obese Humans Demonstrate Increased Vascular Endothelial NAD(P)H Oxidase-p47phox Expression and Evidence of End |
| Notes Main: | NFkB is formed as a homo- or hetero-dimer. Subunits include p50 (NFkB1), p65 (RelA), c-Rel, RelB and p52 (NFkB2). The classic NFkB form exists as a p50-p65 heterodimer and predominates in many cell types. Many of the possible combinatorial forms of homo- |
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