| CatalogCode: | NB600-609 |
| ProductName: | Apolipoprotein A-I Antibody |
| Product Description: | Goat Polyclonal anti-Apolipoprotein A-I |
| Clonality: | Polyclonal |
| Immunogen: | Full length native apoLipoprotein Type A-I (purified). |
| Specificity: | Typically less than 1% cross reactivity against other types of apoLipoprotein was detected by ELISA.This antibody reacts with mouse apoLipoprotein A-I and has negligible cross-reactivity with Type A-II, B, C-I, C-II, C-III, E and J apoLipoproteins. |
| CrossReactivity: | Cross-reacts with Mouse. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Localization: | Secreted |
| Background: | At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A-1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL). Abcam's apo-lipoproteins are derived from human plasma by density gradient ultracentrifugation and HPLC. |
| ProductRef: | 1. Hasebe, A., Pennock, N. D., Mu, H.-H., Chan, F. V., Taylor, M. L., and Cole, B. C. (2006) A Microbial TLR2 Agonist Imparts Macrophage-Activating Ability to Apolipoprotein A-1, 177, 4826-4832. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | 0.15M Sodium Chloride, 0.02M Potassium Phosphate [pH 7] |
| ListPrice: | 245 |
| NovusRef: | 1. Duong. P.T., et al. Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I. J. Lipid Res. 47:832-843, 2006. |
| AppSummary: | ELISA, IHC, WB |
| SpeciesSummary: | Mu |
| ALTnames: | anti-APOA1/APOC3 fusion gene antibody; anti-Apolipoprotein A I precursor antibody; anti-Apolipoprotein of high density lipoprotein antibody |
| ProteinTarget: | Apolipoprotein A-I |
| PackageSize: | 0.1 mg |