| Catalog Code: | NB600-608 |
| Product Type: | Primary Antibody |
| Product Name: | AKT Antibody |
| List Price: | 325 |
| Clonality: | Polyclonal |
| Gene ID: | 207 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-AKT |
| Cross Reactivity: | Cross-reacts with Human. Expected to cross-react with Chicken, Mouse and Rat due to sequence homology. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | Akt (Protein Kinase B, PKB) is a key regulator of many signal transduction pathways (reviewed in ref 1). Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of Akt has been seen in many typ |
| Alternate Names: | anti-CAKT antibody, anti-Murine thymoma viral (vakt) oncogene homolog 1 antibody, anti-PKB Akt antibody, anti-PKB alpha antibody, anti-PKB antibody, anti-PKBalpha antibody, anti-PRKBA antibody, anti-RAC alpha serine/threonine protein kinase antibody, anti |
| Immunogen: | Synthetic peptide with sequence CRPHFPQFSY SASGTA representing the C-terminus (460-480) of human, rat and mouse and chicken Akt proteins. This whole rabbit serum was prepared by repeated immunizations with a KLH conjugated peptide. |
| Localization: | Cytoplasmic and Nuclear |
| Purity: | Whole antisera |
| Buffer: | 0.02 K Phosphate, 0.15M NaCl [pH7.2] |
| Packaging: | 0.2 ml Whole antisera Rabbit antisera. |
| Package Size: | 0.2 ml |
| Uses: | Optimal dilutions should be determined by the end user. |
| Application Summary: | IHC, IF, IP, WB, ICC |
| General References: | Lawlor MA & Alessi DR PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J Cell Sci 114:2903-10 (2001). Alessi DR Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lectu |
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