| Catalog Code: | NB600-426 |
| Product Type: | Primary Antibody |
| Product Name: | mTOR Antibody |
| List Price: | 285 |
| Clonality: | Polyclonal |
| Gene ID: | 2475 |
| Host: | Rabbit |
| Conjugate: | Agarose Immobilized |
| Product Description: | Rabbit Polyclonal anti-mTOR, conjugated Agarose Immobilized |
| Cross Reactivity: | NB 600-426 reacts with human and rat mTOR. Other species have not been tested. |
| Species Summary: | Hu, Rt |
| Background: | FKBP 12 rapamycin associated protein (FRAP) is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. In rat, it is a 235 kDa protein (symbolized RAFT 1) with significant homology to the Saccharomyces |
| Alternate Names: | anti-Cell division cycle 25A isoform a antibody, anti-FK506 binding protein12-rapamycin associated protein 1 antibody, anti-FK506 binding protein12-rapamycin associated protein 2 antibody, anti-FRAP1, anti- FRAP2 antibody, anti-RAFT1 antibody, anti-RAPT1 |
| Immunogen: | A synthetic peptide, which maps to a region between residue 200 and 250 of human Mammalian Target of Rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475).) |
| Specificity: | This antibody is specific for mTOR. |
| Packaging: | 0.4 ml of 50% slurry containing 0.2 ml agarose [0.1 ug antibody/0.2 ml agarose] in 0.01M phosphate, pH 7.2, 0.1M NaCl, with 0.1% sodium azide. |
| Package Size: | 0.4 ml |
| Uses: | Immunoprecipitation Suggested working dilutions: * Immunoprecipitation - 15-25 ul gel slurry per 0.1-1mg protein lysate or extract*The investigator should determine the optimal working dilution for a specific application. |
| Application Summary: | IP |
| Notes Main: | The immunogen for this antibody is from the same region as the immunogen used to immunize animals for NB 600-425. However, the exact sequence for the peptide used to produce NB 600-426 is different from that used for NB 600-425. |