| Catalog Code: | NB600-284SS |
| Product Type: | Primary Antibody |
| Product Name: | WNK4 Antibody |
| List Price: | 95 |
| Clonality: | Polyclonal |
| Gene ID: | 65266 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-WNK4 **Sample Size** |
| Cross Reactivity: | NB 600-284 can be used to detect mouse and human (very weakly) WNK4 protein. |
| Species Summary: | Hu, Mu |
| Background: | WNK kinases play an important role in hypertension. WNK4 localizes to both tight junctions and to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. |
| Immunogen: | A synthetic peptide sequence made to a region of the human protein between residues 200-300. |
| Specificity: | NB 600-284 is specific for WNK4 protein. |
| Packaging: | 0.025 ml Rabbit antisera. |
| Package Size: | 0.025 ml |
| Concentration: | 0.92 mg/ml |
| Uses: | This antibody is useful for Western blot where a band is seen at ~135-155 kD. No other applications have been tested. Suggested working dilutions: * Western Blot - 2 ug/ml (ECL) *The investigator should determine the optimal dilution for a specific applic |
| Application Summary: | WB |
| General References: | 1. Wilson, F.H., et al. Science 293: 1107-1112 (2001) |
| Product References: | 1. Song, J., Hu, X., Riazi, S., Tiwari, S., Wade, J. B., and Ecelbarger, C. A. (2006) Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats, 290, F1055-1064. |
| Novus References: | 1. Song, J., et al. Regluation of blood pressure, the epithelial sodium channel (ENaC) and other key renal sodium transporters by chornic insulin infusion in rats. Am. J. Physiol. Renal Physiol. 290:1055-1064, 2006.2. Kahle, K.T., et al. WNK4 regulates ap |
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