| Catalog Code: | NB600-1498 |
| Product Type: | Primary Antibody |
| Product Name: | IFN gamma Antibody |
| List Price: | 295 |
| Clonality: | Monoclonal |
| Gene ID: | 3458 |
| Host: | Mouse |
| Clone: | F12 |
| Isotype: | IgG1 |
| Product Description: | Mouse Monoclonal anti-IFN gamma (F12) |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Species Summary: | Hu |
| Localization: | Secreted |
| Specificity: | Monoclonal antibody F14 binds and neutralizes both natural and recombinant human gamma Interferon. Cross-reactivity with other cytokines has not been found. In general, monoclonal antibodies to gamma Interferon are able to inhibit Shwartzman reactions (re |
| Purity: | IgG purified |
| Buffer: | PBS |
| Packaging: | 0.05 mg IgG purified Mouse ascites. |
| Package Size: | 0.05 mg |
| Uses: | The antibody binds and neutralizes both natural and recombinant human gamma Interferon. The specific activity is approximately 5 x 10<sup>3</sup> neutralizing units<sup>1</sup>/mg antibody. The antibody is also useful as a detectio |
| Application Summary: | ELISA, IHC-FR, |
| General References: | General / background references:Billiau A Gamma-interferon: the match that lights the fire? Immunol Today 9:37-40 (1988). Jacob CO et al. In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon. |
| Notes Main: | One neutralizing unit is defined as the amount of antibody sufficient for neutralizing one unit of human gamma Interferon as calibrated against NIH standard Gg23-901-530. For the determination of the neutralizing activity a cytopathic inhibition assay was |