| CatalogCode: | NB600-1423 |
| ProductName: | CD36 Antibody |
| Product Description: | Mouse Monoclonal anti-CD36 (FA6-152) |
| Clone: | FA6-152 |
| Clonality: | Monoclonal |
| Immunogen: | Fetal erythrocytes. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.5 ml IgG purified Mouse ascites. |
| Uses: | BL: Use at an assay dependent dilution (blocks collagen/thrombospondin binding. WB: Predicted molecular weight: 88 kDa. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Integral membrane protein. |
| Background: | CD36 is a cell surface class B scavenger receptor. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signalling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cyto adherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | IgG purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | PBS containing 0.1% BSA |
| ListPrice: | 325 |
| NovusRef: | 1. During A, Doraiswamy S, Harrison EH. Xanthophylls are preferentially taken up compared to beta -carotene by retinal cells via a scavenger receptor BI-dependent mechanism. J Lipid Res. April 19, 2008:M700580-JLR200. |
| AppSummary: | FACS, IP, WB, IHC-Fr |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Platelet glycoprotein IV antibody, anti-Synonyms GPIV antibody, anti-Glycoprotein IIIb antibody, anti-GPIIIB antibody, anti-Leukocyte differentiation antigen CD36 antibody, anti-CD36 antigen antibody, anti-PAS IV antibody, anti-PAS-4 protein antibody, anti-Platelet collagen receptor antibody |
| ProteinTarget: | CD36 |
| PackageSize: | 0.5 ml |
| GeneralRef: | General / background references:Thibert V et al. Quantitation of platelet glycoprotein IV (CD36) in healthy subjects and in patients with essential thrombocythemia using an immunocapture assay. Thromb Haemost 68:600-5 (1992). Kieffer N et al. Developmentally regulated expression of a 78 kDa erythroblast membrane glycoprotein immunologically related to the platelet thrombospondin receptor. Biochem J 262:835-42 (1989). Edelman P et al. A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors. Blood 67:56-63 (1986). |