| CatalogCode: | NB600-1346 |
| ProductName: | WTAP Antibody |
| Product Description: | Chicken Polyclonal anti-WTAP |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: MTNEEPLPKK VRLSETDFKV MARDELILRW KQYEAYVQAL EGKYTDLNSN DVTGLRESEE KLKQQQQESA RRENILVMRL ATKEQEMQEC TTQIQYLKQV QQPSVAQLRS TMVDPAINLF FLKMKGELEQ TKDKLEQAQN ELSAWKFTPDS, corresponding to amino acids 1-151 of KIAA0105. |
| CrossReactivity: | Cross-reacts with Human, Mouse and Rat. Expected to cross-react with Zebrafish (80% identity with immunogen) due to sequence homology.Not yet tested in other species. |
| Packaging: | 0.05 mg Immunogen affinity purified Chicken antisera. |
| Uses: | IHC: Use at a dilution of 1/200. WB: Use at a dilution of 1/2000. Predicted molecular weight: 44 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear and Nucleolar |
| Control: | E coli-derived fusion protein |
| Background: | Wilms' tumour 1 associating protein plays a role in both transcriptional and post transcriptional regulation of certain cellular genes. This protein is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of its gene results in three transcript variants, two of which encode the same isoform. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgY |
| Host_Name: | Chicken |
| Buffer: | Preservative: None Constituents: PBS |
| ListPrice: | 295 |
| AppSummary: | IHC, WB |
| SpeciesSummary: | Hu, Mu, Rt |
| ALTnames: | anti-DKFZp686F20131 antibody, anti-KIAA0105 antibody, anti-MGC3925 antibody, anti-PNAS 132 antibody, anti-PNAS132 antibody, anti-Putative pre mRNA splicing regulator female lethal(2D) antibody, anti-Putative pre-mRNA splicing regulator female lethal 2D homolog antibody, anti-Putative pre-mRNA splicing regulator female lethal(2D) homolog antibody, anti-Wilms tumor 1 associated protein antibody, anti-Wilms tumor 1 associating protein antibody, anti-Wilms' tumor 1 associating protein antibody, anti-WT1 associated protein antibody |
| ProteinTarget: | WTAP |
| PackageSize: | 0.05 mg |
| GeneralRef: | General / background references:Little NA et al. Identification of WTAP, a novel Wilms' tumour 1-associating protein. Hum Mol Genet 9:2231-9 (2000). |
| NotesMain: | During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 uL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap. |