| Catalog Code: | NB600-1310 |
| Product Type: | Primary Antibody |
| Product Name: | Ezrin Antibody |
| List Price: | 295 |
| Clonality: | Monoclonal |
| Gene ID: | 7430 |
| Host: | Mouse |
| Clone: | 3C12 |
| Isotype: | IgG1 |
| Product Description: | Mouse Monoclonal anti-Ezrin (3C12) |
| Cross Reactivity: | Cross-reacts with Human, Rat, Mouse, Cow, Hamster, Monkey and Kangaroo. Not yet tested in other species. |
| Species Summary: | Hu, Mk, Bv, Rt, Mu, Ha, Other |
| Background: | Ezrin serves as a tyrosine kinase substrate and is phosphorylated in EGF-stimulated cells. It is a cytoplasmic protein enriched in microvilli and other cell surfaces. Ezrin has an actin-binding capacity and is expressed in epithelial cells but not in mese |
| Immunogen: | Recombinant fragment, corresponding to amino acids 362-585 of Human Ezrin. |
| Specificity: | This antibody detects a protein of 81 kDa. |
| Purity: | IgG purified |
| Buffer: | PBS with sodium azide |
| Packaging: | 500 microlitres Liquid. |
| Package Size: | 0.5 ml |
| Uses: | Immunohistochemistry: use at a dilution of 1/50 - 1/100 for 30mins at RT (ABC method). Not tested in other applications.Optimal dilutions / concentrations should be determined by the end user.For formalin fixed paraffin embedded sections, perform heat med |
| Application Summary: | IHC-Fr, IHC-P, WB |
| General References: | General / background references:Bohling T et al. Ezrin expression in stromal cells of capillary hemangioblastoma. An immunohistochemical survey of brain tumors. Am J Pathol 148:367-73 (1996). Helander TS et al. ICAM-2 redistributed by ezri |