| Catalog Code: | NB600-1287 |
| Product Type: | Primary Antibody |
| Product Name: | FGF Receptor 1 Antibody |
| List Price: | 295 |
| Clonality: | Monoclonal |
| Gene ID: | 2260 |
| Host: | Mouse |
| Clone: | M19B2 |
| Isotype: | IgG1 |
| Product Description: | Mouse Monoclonal anti-FGF Receptor 1 (M19B2) |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Species Summary: | Hu |
| Immunogen: | Recombinant human ectodomain of FGFr1b expressed in E. coli beginning with proline 23; antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences. |
| Epitope: | Epitope is within the NH2-terminus of Ig loop II sequence lys145 and glu159 between the acidic box and heparin-binding sequence of FGFr1. |
| Specificity: | Reacts with both alpha and beta isoforms. |
| Purity: | Protein G purified |
| Buffer: | PBS with 0.02% sodium azide |
| Packaging: | 125 micrograms |
| Package Size: | 0.125 mg |
| Uses: | Western blotting: at 1 ug/ml recognizes 10 ng recombinant bacterial, baculo-viral, or native FGFr1.Immunoprecipitation: native, recombinant, and ligand-labeled FGFr1.Immunohistochemistry: paraformalde-hyde fixed cells.For all applications, user must deter |
| Application Summary: | FACS, IHC-P, IP, WB |
| General References: | This product has been used in:Aziz KA et al. The role of autocrine FGF-2 in the distinctive bone marrow fibrosis of hairy-cell leukemia (HCL). Blood 102:1051-6 (2003). General / background references:Feng S et al. Nuclear localization of |