| CatalogCode: | NB600-1231 |
| ProductName: | NALP3 Antibody |
| Product Description: | Mouse Monoclonal anti-NALP3 (Nalpy3-a) |
| Clone: | Nalpy3-a |
| Clonality: | Monoclonal |
| Immunogen: | Recombinant full length protein (Human). |
| Specificity: | Recognises endogenous human NALP3. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.5 mg |
| Uses: | WB: Predicted molecular weight: 124 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Constituents: PBS |
| ListPrice: | 325 |
| AppSummary: | WB, ICC |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Cryopyrin antibody; anti-PYPAF1 antibody; anti-CIAS1 antibody |
| ProteinTarget: | NALP3 |
| PackageSize: | 0.05 mg |
| GeneralRef: | General / background references:Martinon F & Tschopp J Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117:561-74 (2004). Chamaillard M et al. Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation. Cell Microbiol 5:581-92 (2003). O'Connor W et al. Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties. J Immunol 171:6329-33 (2003). |
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