| Catalog Code: | NB600-1179 |
| Product Type: | Primary Antibody |
| Product Name: | FRS2 Antibody |
| List Price: | 325 |
| Clonality: | Polyclonal |
| Gene ID: | 10818 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-FRS2 |
| Cross Reactivity: | Cross-reacts with Human, Mouse and Rat. Not yet tested in other species. |
| Species Summary: | Hu, Mu, Rt |
| Background: | FGFs (Fibroblast Growth Factors) bind to FGF receptors (FGFRs) monovalently, and FGF receptor dimerization and activation is mediated by multivalent interactions between heparin sulfate proteoglycans and FGF. Upon activation, receptor tyrosine kinases un |
| Alternate Names: | anti-FRS2A antibody, anti-FRS2alpha antibody, anti-SNT antibody, anti-SNT-1 antibody, anti-SNT1 antibody |
| Immunogen: | Synthetic peptide conjugated to KLH, corresponding to amino acids 487-505 of Human FRS2alpha. |
| Purity: | Immunogen affinity purified |
| Buffer: | 0.01M PBS [pH7.4] with 1% BSA containing 15 mM sodium azide |
| Packaging: | 0.1 ml purified antisera. |
| Package Size: | 0.1 ml |
| Concentration: | 2 mg/ml |
| Uses: | This antibody can be used in Immunoprecipitation and Western Blot. By Western Blot 92 and 95kDa bands are seen. Recommended Starting Dilutions*: IP: WB: 1/1000. *Optimal dilutions should be determined by the end user. |
| Application Summary: | IP, WB |
| General References: | Kouhara H et al. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89:693-702 (1997). Schlessinger J et al. Regulation of growth factor activation by proteoglycans: what is the |