| CatalogCode: | NB600-1176 |
| ProductName: | PKR Antibody |
| Product Description: | Rabbit Monoclonal anti-PKR (YE350) |
| Clone: | YE350 |
| Clonality: | Monoclonal |
| Immunogen: | A synthetic peptide corresponding to residues following the first double-stranded RNA-binding domain of human PKR was used as immunogen. |
| Specificity: | The antibody does not cross-react with other GCN2 family members. |
| CrossReactivity: | Reacts with Human PKR results have been mixed in detecting the mouse and rat protein. Not yet tested in other species. |
| Packaging: | 0.1 ml IgG purified Rabbit ascites. |
| Uses: | Optimal dilutions should be determined by the end user. |
| Localization: | Cytoplasmic |
| Control: | HeLa cell lysate and cells and human stomach carcinoma. |
| Background: | Protein kinase R (PKR) is a serine/threonine kinase that is induced by interferon and activated by double-stranded RNA. Upon activation, PKR is autophosphorylated at multiple sites and phosphorylates the |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | 50 mM Tirs-glycine [pH7.4] with 40% Glycerol, 0.05% BSA & 0.15M Sodium chloride |
| ListPrice: | 325 |
| AppSummary: | IHC, IP, WB, ICC |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Double Stranded RNA Activated Interferon Inducible Protein Kinase antibody, anti-EIF2AK1 antibody, anti-Interferon inducible elF2 alpha kinase antibody, anti-P1/eIF2A protein kinase antibody, anti-p68 kinase antibody, anti-PRKR antibody |
| ProteinTarget: | PKR [YE350] |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Williams, B.R. PKR; a sentinel kinase for cellular stress. Oncogene 18: 6112 |