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| Catalog Code: | NB600-1161 |
| Product Name: | Jagged1 Antibody |
| Product Description: | Rabbit Polyclonal anti-Jagged1 |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Concentration: | 1.17 mg/ml |
| Immunogen: | Synthetic peptide: KASRGNDRNRIVLPFS-C conjugated to KLH, corresponding to amino acids 110-125 of Human Jagged1. |
| Cross Reactivity: | Expected to cross-react with Human (100% identity with immunogen), Mouse (100% identity with immunogen) and Rat (100% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.5 mg protein A purified Rabbit antisera. |
| Uses: | Western blot: expected band size is 134kDa and a band slightly less than 50kDa is detected in mouse liver lysate. Additional positive control data is required. Tested in peptide ELISA. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Type I membrane protein. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | protein A purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
| Application Summary: | ELISA , Western Blot |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | Anti-AGS antibody, Anti-AHD antibody, Anti-AWS antibody, Anti-CD 339 antibody, Anti-CD339 antibody, Anti-CD339 antigen antibody, Anti-Headturner antibody, Anti-HJ1 antibody, Anti-Htu antibody, Anti-Jag 1 antibody, Anti-Jag1 antibody, Anti-Jagged 1 antibody, Anti-Jagged1 (Alagille syndrome) antibody, Anti-JAGL1 antibody, Anti-MGC104644 antibody, Anti-Ser-1 antibody, Anti-Serrate-1 antibody, Anti-Slalom antibody |
| Package Size: | 0.5 mg |
| Preservative: | 0.01% Sodium Azide |
| General References: | Proweller A et al. Notch signaling represses myocardin-induced smooth muscle cell differentiation. J Biol Chem : (2005). Mancini SJ et al. Jagged1 dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood : (2004). Stidworthy MF et al. Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain 127:1928-41 (2004). Kostyszyn B et al. Distribution of presenilin 1 and 2 and their relation to Notch receptors and ligands in human embryonic/foetal central nervous system. Brain Res Dev Brain Res 151:75-86 (2004). |
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