| CatalogCode: | NB500-619 |
| ProductName: | CD22 Antibody |
| Product Description: | Mouse Monoclonal anti-CD22 (MEM-01), conjugated PE |
| Clone: | MEM-01 |
| Clonality: | Monoclonal |
| Immunogen: | Burkitt's lymphoma cell line Raji. |
| Specificity: | NB 500-619 recognises CD22. |
| CrossReactivity: | Reacts with Human and Non Human Primates. Not yet tested in other species. |
| Packaging: | 2 ml IgG1 purified antisera. |
| Uses: | This antibody can be used for FACS. Not tested in other applications.Recommended starting dilutions:*FACS: Use 20ul for 106 cells or 100ul of whole blood.*Optimal dilutions/concentrations should be determined by the end user. |
| Background: | CD22 is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140kD. It is expressed in both the cytoplasm and cell membrane of B lymphocytes. CD22 antigen appears early in B cell lymphocyte differentiation at approximately the same stage as the CD19 antigen. Unlike other B cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias. CD22 is also strongly expressed in hairy cell leukemia. There are two different isoforms of CD22. It exists predominantly as a monomer of the beta isoform but can also be found as a heterodimer composed of the beta isoform and a second, shorter isoform (CD22 alpha). |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | IgG purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Preservative: 15mM Sodium Azide. Constituents: 0.2% high-grade protease free BSA, PBS |
| ListPrice: | 285 |
| AppSummary: | FACS |
| SpeciesSummary: | Hu |
| ALTnames: | anti-B cell receptor CD22 precursor antibody, anti-B lymphocyte cell adhesion molecule antibody, anti-BLCAM antibody, anti-CD22 antigen antibody, anti-Leu14 antibody, anti-Lyb8 antibody, anti-Sialic acid binding immunoglobulin like lectin 2 antibody, anti-SIGLEC2 antibody |
| ProteinTarget: | CD22 prediluted |
| PackageSize: | 2 ml (100 tests) |
| Conjugate: | PE |
| GeneralRef: | Unpublished. |