| Catalog Code: | NB500-597 |
| Product Type: | Primary Antibody |
| Product Name: | IRAK4 Antibody |
| List Price: | 325 |
| Clonality: | Polyclonal |
| Gene ID: | 51135 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-IRAK4 |
| Cross Reactivity: | Cross-reacts with Human and Mouse. Not yet tested in other species. |
| Species Summary: | Hu, Mu |
| Background: | The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Dro |
| Alternate Names: | anti-IRAK4 antibody, anti-REN64 antibody, anti-NY-REN-64 antibody, anti-interleukin-1 receptor-associated kinase 4 antibody, anti-IRAK-4 mutated form 1 antibody, anti-interleukin-1 receptor associated kinase 4 antibody, anti-interleukin-1 receptor associa |
| Immunogen: | This antibody was developed against a mixture of synthetic peptides containing amino acids 38-54 and 120-136 of mouse IRAK-4. |
| Localization: | Cell Membrane |
| Purity: | Protein G purified |
| Buffer: | PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic. |
| Packaging: | 200 microlitres |
| Package Size: | 0.2 ml |
| Concentration: | 0.5 mg/ml |
| Uses: | WB: Use at a dilution of 1/500 - 1/1000. Detects a band of approximately 51 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | WB |
| General References: | General / background references:Li S et al. IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc Natl Acad Sci U S A 99:5567-72 (2002). Suzuki N et al. Severe impairment of interleukin-1 and Toll-like rece |