| CatalogCode: | NB500-586 |
| ProductName: | HLA ABC Antibody |
| Product Description: | Mouse Monoclonal anti-HLA ABC (W6/32), conjugated to Biotin |
| Clone: | W6/32 |
| Clonality: | Monoclonal |
| Immunogen: | Purified human tonsil lymphocyte membranes |
| Specificity: | NB 500-586 recognizes a monomorphic determinant (alpha chain) of major histocompatibility HLA Class I antigens (HLA-A, B, C antigen). |
| CrossReactivity: | Reacts with Human. Not yet tested in other species |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | This antibody can be used for FACS and ICC. Not tested in other applications.Recommended starting dilutions:*FACS: Use 1ug for 106 cells.ICC: Acetone fixed tissue sections. Use at an assay dependent dilution. *Optimal dilutions/concentrations should be determined by the end user |
| Background: | Major histocompatibility antigen class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. This antibody may be used to identify the expression of HLA-A, B, C gene products |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | protein G purified |
| Isotype: | IgG2a |
| Host_Name: | Mouse |
| Buffer: | Preservative: 0.09% Sodium Azide, Constituents: 1% BSA, 0.01M PBS. pH 7.2 |
| ListPrice: | 295 |
| AppSummary: | FACS, ICC |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Antigen Presenting Molecule antibody, anti-HLA Class I Histocompatibility Antigen A Alpha Chain antibody, anti-HLA Class I Histocompatibility Antigen B Alpha Chain antibody, anti-HLA Class I Histocompatibility Antigen C Alpha Chain antibody, anti-Human Leucocyte Antigen C antibody, anti-Major Histocompatibility Complex Class I A antibody, anti-Major Histocompatibility Complex Class I B antibody, anti-Major Histocompatibility Complex Class I C antibody, anti-MHC Class I Antigen antibody |
| ProteinTarget: | HLA ABC |
| PackageSize: | 0.1 mg |
| Conjugate: | Biotin |
| GeneralRef: | Brodsky FM et al. Monoclonal antibodies for analysis of the HLA system. Immunol Rev 47:3-61 (1979). PubMed: 95015 Barnstable CJ et al. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell 14:9-20 (1978). PubMed: 667938 Search PubMed (MEDLINE) for references to HLA ABC |