| CatalogCode: | NB500-465 |
| ProductName: | TRAIL Antibody |
| Product Description: | Mouse Monoclonal anti-TRAIL (2E5) |
| Clone: | 2E5 |
| Clonality: | Monoclonal |
| Immunogen: | Recombinant soluble fragment, corresponding to amino acids 95-281 of Human TRAIL. |
| Specificity: | This antibody is specific for TRAIL, Tumour necrosis factor (TNF) related apoptosis inducing ligand (TRAIL/ APO2-L)). |
| CrossReactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.1 mg PBS, preserved by filter sterilization. |
| Uses: | FuncS: Use at an assay dependent concentration. Has high neutralizing activity for human TRAIL in biological assays.Neutralizing activity was tested in Jurkat T cells, where apoptosis was induced by a recombinant human soluble TRAIL (300 ng/ml), it completely neutralizes rhsTRAIL mediated killing in a concentration range of 0.5-1.5ug/ml). Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cell Membrane |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Preservative: NoneConstituents: PBS. pH 7.4 |
| ListPrice: | 285 |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Apo 2 ligand antibody, anti-Apo 2L antibody, anti-APO2L antibody, anti-CD253 antibody, anti-TL2 antibody, anti-TNF Related Apoptosis Inducing Ligand antibody, anti-TNFSF10 antibody, anti-TRAIL antibody, anti-TRAIL PEN antibody,, anti- Tumor Necrosis Factor (ligand) Superfamily Member 10 antibody |
| ProteinTarget: | TRAIL |
| PackageSize: | 0.1 mg |
| GeneralRef: | This product has been used in:Plasilova M et al. TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasia progenitors. Leukemia 16:67-73 (2002). |