| CatalogCode: | | NB500-332 |
| ProductName: | | Insulin Antibody |
| Product Description: | | Mouse Monoclonal anti-Insulin (IN-05) |
| Clone: | | IN-05 |
| Clonality: | | Monoclonal |
| Immunogen: | | Full length native protein (purified) (Pig). |
| Specificity: | | Blocks binding of insulin to its receptor. |
| CrossReactivity: | | Cross-reacts with Human, Cow and Pig. Not yet tested in other species. |
| Packaging: | | 0.1 mg Liquid |
| Uses: | | ELISA: Use at an assay dependant dilution. FuncS: Use at an assay dependant dilution. Antibody blocks binding of insulin to the receptor. ICC: Use at an assay dependant dilution. IHC-P: Use at an assay dependant dilution. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. RIA: Use at an assay dependant dilution. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | | Secreted |
| Background: | | Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | Affinity purified |
| Isotype: | | IgG1 |
| Host_Name: | | Mouse |
| Buffer: | | 15mM Sodium Azide in PBS. pH 7.4 |
| ListPrice: | | 285 |
| AppSummary: | | ELISA, ICC, IHC-P, RID |
| SpeciesSummary: | | Hu, Bv, Po |
| ALTnames: | | anti-Insulin precursor antibody |
| ProteinTarget: | | Insulin |
| PackageSize: | | 0.1 mg |
| GeneralRef: | | Horejsi |
| more information: | | company product webpage |