| Catalog Code: | NB500-317 |
| Product Type: | Primary Antibody |
| Product Name: | Beta-2-microglobulin Antibody |
| List Price: | 275 |
| Clonality: | Monoclonal |
| Gene ID: | 567 |
| Host: | Mouse |
| Clone: | B2M-01 |
| Isotype: | IgG2a |
| Product Description: | Mouse Monoclonal anti-Beta-2-microglobulin (B2M-01) |
| Cross Reactivity: | Cross-reacts with Human. Does not cross-react with Chicken, Cow, Dog, Mouse, Pig or Rabbit. Not yet tested in other species. Weak positive staining was observed in peripheral blood lymphocytes of the monkey Cercopithecus aethiops. |
| Species Summary: | Bv(-), Ca(-), Ch(-), Hu, Mu(-), Po(-), Rb(-) |
| Background: | Beta 2 Microglobulin non covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, mon |
| Alternate Names: | anti-B2M antibody, anti-Beta 2 microglobulin precursor antibody, anti-Beta chain of mhc class 1 proteins antibody, anti-Hdcma22p antibody |
| Immunogen: | Full length native protein (purified) (Human). |
| Specificity: | This antibody reacts with beta-2-microglobulin, associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble forms of beta-2-microglobulin. |
| Purity: | Affinity purified |
| Buffer: | In PBS with 15mM Sodium Azide. pH 7.4 |
| Packaging: | 0.1 mg |
| Package Size: | 0.1 mg |
| Uses: | RIA: Dissociation constant of the antibody-soluble b2-microglobulin is 1.5 x 10<sup>-8</sup> mol/l as determined by competitive RIA.Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | ELISA, FACS, IP, RIA, WB |
| General References: | Hilgert I et al. The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin. Folia Biol (Praha) 30:369-76 (1984). |