| CatalogCode: | NB500-267 |
| ProductName: | Histone H3 Antibody |
| Product Description: | Rabbit Polyclonal anti-Histone H3 |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Histone H3. |
| Specificity: | This antibody is specific for Histone H3. |
| CrossReactivity: | Cross-reacts with human and mouse. Expected to cross-react with all Mammals and a wide range of other species due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 ml IgG purified Rabbit antisera. |
| Uses: | This antibody may be used for Western blot, where a band is seen ~17 kDa. Optimal working dilutions should be determined by the investigator. |
| Localization: | Nuclear |
| Control: | MEF and HeLa lysates |
| Background: | In diploid eukaryotic cells, the chromatin fibers are about 20nM in diameter. They consist of two major components in equal amounts, DNA and basic proteins called histones. Histones are believed to be regularly arranged in the deep grove of the DNA helix. The recurring positive charges of the histones form electrostatic associations with the negatively charged phosphate groups of DNA making the DNA more stable and flexible. This allows for the supercoiling of the chromatin fibers. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Host_Name: | Rabbit |
| Buffer: | PBS |
| ListPrice: | 285 |
| NovusRef: | Karagianni, P., et al. ICBP90, a Novel Methyl K9 H3 Binding Protein Linking Protein Ubiquitination with Heterochromatin Formation. Mol. Cell. Biol., Jan 2008; 28: 705-717. |
| AppSummary: | WB |
| SpeciesSummary: | Hu, Mu |
| ALTnames: | anti-H3 antibody; anti-HisH3 antibody; anti-His1H3 antibody; anti-H3/a antibody; anti-H3/b antibody; anti-H3 antibody; anti-c antibody; anti-H3/d antibody; anti-H3/f antibody; anti-H3/h antibody; anti-H3/i antibody; anti-H3/j antibody; anti-H3/k antibody; anti-H3/l antibody; anti-Histone H3 antibody |
| ProteinTarget: | Histone H3 |
| PackageSize: | 0.1 ml |