| Catalog Code: | NB500-254 |
| Product Type: | Primary Antibody |
| Product Name: | Bcl-xL Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 598 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-Bcl-xL |
| Cross Reactivity: | Human. Other species not tested. Reactivity with mouse and rat Bcl-xL is expected based upon complete identity between these orthologs and human Bcl-xL at the site to which the epitope maps. |
| Species Summary: | Hu |
| Background: | Bcl xL is a 241 amino acid 28 kDa member of Bcl2 family of proteins and an important regulator of apoptosis. Bcl xL forms heterodimers with BAX, BAK, and Bcl2, and its overexpression in tumor cells confers resistance against chemotherapeutic drugs. Bcl xL |
| Alternate Names: | anti-ecotropic viral integration site 9 antibody |
| Immunogen: | A synthetic peptide which maps to a region between residues 1 and 50 of human BCL2-like 1 using the numbering given in SwissProt entry Q07817 (GeneID 598). |
| Specificity: | NB 500-254 is specific for human Bcl-xl protein. |
| Packaging: | 0.1 ml of affinity purified rabbit sera in a Tris-citrate/phosphate (pH 7-8) buffer with 0.1% sodium azide. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested starting dilutions are as follows. Western Blot: 1:10,000 - 1:25,000 Immunoprecipitation: not tested Histo/Cy |
| Application Summary: | WB |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |