| CatalogCode: | NB500-242 |
| ProductName: | TRPM2 Antibody |
| Product Description: | Rabbit Polyclonal anti-TRPM2 |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide, which represented a portion of human transient receptor potential cation channel, subfamily M, member 2 encoded within exon 13 (LocusLink ID 7226). |
| Specificity: | This antibody is specific for TRPM2. |
| CrossReactivity: | NB 500-242 recognizes human TRPM2. Other species have not been tested. Reactivity with mouse and rat are likely due to conservation of this ortholog with the peptide used for this antibody production. |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Uses: | The investigator should determine the optimal working dilution for a specific application. |
| Background: | TRPM2 is a Ca(2+)-permeable channel that is activated by oxidative stress and confers susceptibility to cell death. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate buffer pH7-8 |
| ListPrice: | 300 |
| NovusRef: | Partida-Sanchez, S., et al. Chemotaxis of Mouse Bone Marrow Neutrophils and Dendritic Cells is Controlled by ADP-Ribose, the Major Product Generated by the CD38 Enzyme Reaction. J. Immunol., Dec 2007; 179: 7827-7839. Anelli VV, Gault CR, Cheng AB, Obeid LM. Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells: Role of hypoxia-inducible factors 1 and 2. J Biol Chem. 2007 November 30, 2007:M708241200. |
| AppSummary: | IF, IP, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-EREG1 antibody, anti-KNP3 antibody, anti-LTRPC2 antibody, anti-putative Ca2+ channel protein antibody, anti-transient receptor potential cation channel subfamily M member 2 antibody, anti-TRPC7 antibody |
| ProteinTarget: | TRPM2 |
| PackageSize: | 0.1 ml |
| NotesMain: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |