| Catalog Code: | NB500-239 |
| Product Type: | Primary Antibody |
| Product Name: | E6AP Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 7337 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-E6AP |
| Cross Reactivity: | NB 500-239 recognizes human. Other species have not been tested. Reactivity with mouse is likely owing to sequence homology with the immunogen used for this antibody. |
| Species Summary: | Hu |
| Background: | E6AP was originally identified as the ubiquitin-protein ligase involved in human papillomavirus E6-mediated p53 degradation. It has since been shown to act as an E3 ubiquitin-protein ligase catalyzing the ubiquitination of several other protein substrate |
| Immunogen: | A synthetic peptide made to a portion of human ubiquitin protein ligase E3A encoded within exon 6 (LocusLink ID 7337). |
| Specificity: | This antibody is specific for E6AP. |
| Purity: | Affinity purified |
| Packaging: | 0.1 ml of rabbit antisera (1 mg/ml) with sodium azide. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | This antibody has been shown to immunoprecipitate E6AP in HeLa extracts (better in cytosolic preparations where the major IP component is the phosphorylase kinase complex). It also recognizes a band at ~104 kDa in Western blot, representing E6AP (in cytos |
| Application Summary: | IP, WB |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |