| Catalog Code: | NB500-191 |
| Product Type: | Primary Antibody |
| Product Name: | XRN1 Antibody |
| List Price: | 300 |
| Clonality: | Polyclonal |
| Gene ID: | 54464 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-XRN1 |
| Cross Reactivity: | Human. Other species have not been tested. Reactivity with mouse XRN1 is expected owing to identity of sequence between this ortholog and human XRN1 at the site to which the epitope maps. |
| Species Summary: | Hu |
| Background: | SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere main |
| Alternate Names: | anti-XRN1 antibody, anti-XRN-1 antibody, anti-5-3 Exoribonuclease 1 antibody, anti-SEP1 antibody, anti-SEP-1 antibody, anti-Strand Exchange Protein 1 antibody |
| Immunogen: | A synthetic peptide, mapping to a region region between residue 1650 and the C-terminus (residue 1706) of human 5'-3' Exoribonuclease 1 using the numbering given in TrEMBL entry Q6MZS8 (GeneID 54464). |
| Specificity: | NB 500-191 is specific for human XRN1/SEP1. |
| Buffer: | Tris-citrate/phosphate buffer [pH7-8] containing 0.09% sodium azide |
| Packaging: | 0.1 ml purified antisera. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | This antibody can be used in Western Blot and Immunoprecipitation. Recommended Starting Dilutions*: WB: 1:5,000 - 1:15,000 IP: 2 to 5 ug/mg lysate*Optimal dilutions should be determined by the end user. |
| Application Summary: | WB, IP |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |