| CatalogCode: | NB500-185 |
| ProductName: | Aurora B Antibody |
| Product Description: | Rabbit Polyclonal anti-Aurora B |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide, mapping to a region region between residue 300 and the C-terminus (residue 344) of human Aurora B kinase using the numbering given in Swiss-Prot entry Q96GD4 (GeneID 9212). |
| Specificity: | NB 500-185 is specific for human Aurora B protein. |
| CrossReactivity: | Human. Other species have not been tested. Reactivity with mouse Aurora B is unlikely owing to divergence of sequence between this ortholog and human Aurora B at the site to which the epitope maps. |
| Packaging: | 0.1 ml Rabbit antisera. |
| Uses: | NB 500-185 may be used for Western blot, immunofluorescence, and immunoprecipitation.Suggested working dilutions: *Western Blot: 1:5,000 - 1:15,000 Immunoprecipitation: 1 to 4 ug/mg lysate Immunofluorescence: 0.5 to 2 ug/ml*The investigator should determine the optimal working dilution for a specific application. |
| Background: | Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A (MIM 603072) localizes to centrosomes (Lampson et al., 2004).[supplied by OMIM] |
| Storage: | Store at 4C. Do not freeze. |
| Host_Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate [pH7-8] containing 0.09% sodium azide |
| ListPrice: | 285 |
| AppSummary: | IF, IP, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-AIK2 antibody, anti-AIM1 antibody, anti-ARK2 antibody, anti-AURKB antibody, anti-Aurora 1 antibody, anti-Aurora kinase B antibody, anti-Aurora- and Ipl1-like midbody-associated protein 1 antibody, anti-Aurora-related kinase 2 antibody, anti-Aurora/IPL1 related kinase 2 antibody, anti-IPL1 antibody |
| ProteinTarget: | Aurora B |
| PackageSize: | 0.1 ml |
| NotesMain: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |
| Gene_Id: | 9212 |
| Omim_ID: | NB100-1729 |