| Catalog Code: | NB500-106 |
| Product Type: | Primary Antibody |
| Product Name: | PCNA Antibody |
| List Price: | 275 |
| Clonality: | Monoclonal |
| Gene ID: | 5111 |
| Host: | Mouse |
| Clone: | PC10 |
| Isotype: | IgG2a |
| Product Description: | Mouse Monoclonal anti-PCNA (PC10) |
| Cross Reactivity: | Human, Yeast (S. pombe and S. cerevisiae), Drosophila melanogaster, Rat, Mouse, and Chicken |
| Species Summary: | Hu, Ye, Dr, Rt, Mu, Ch |
| Background: | PCNA, also known as polymerase delta auxiliary protein, is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine |
| Alternate Names: | anti-Cyclin antibody, anti-DNA polymerase delta auxiliary protein antibody, anti-HGCN8729 antibody, anti-MGC8367 antibody, anti-polymerase delta accessory protein antibody, anti-Proliferating Cell Nuclear Antigen antibody |
| Immunogen: | Proliferating cell nuclear antigen, (PCNA), also known as cyclin or polymerase delta accessory protein |
| Specificity: | Specific for PCNA p36 protein expressed at high levels in proliferating cells. |
| Purity: | protein A purified |
| Buffer: | Phosphate buffered saline |
| Packaging: | 0.1 mg protein A purified Mouse ascites. |
| Package Size: | 0.1 mg |
| Uses: | This antibody has been tested in Immunohistochemistry (Paraffin embedded), Immunoprecipitation, and Western blot. It detects a band at 30 kDa by Western blot. For IHC on parafin sections heat-mediated citrate buffer antigen retrieval is recommended. |
| Application Summary: | IHC, IP, WB |
| Product References: | 1. Waseem N and Lane DJ. 1990. Cell Sci. 96:121-129 2. Woods AL et al. 1991. Histopathol. 19:21-27 29-33. |
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