| Catalog Code: | NB400-165 |
| Product Type: | Primary Antibody |
| Product Name: | ABCA1 Antibody |
| List Price: | 275 |
| Clonality: | Monoclonal |
| Gene ID: | 11303 |
| Host: | Rat |
| Clone: | 5A1-1422.11 |
| Isotype: | IgG2a kappa |
| Product Description: | Rat Monoclonal anti-ABCA1 (5A1-1422.11) |
| Cross Reactivity: | This antibody reacts with mouse ABCA1. Other species have not been tested. |
| Species Summary: | Mu |
| Background: | Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system |
| Alternate Names: | anti-ABC 1 antibody, anti-ABC Transporter 1 antibody, anti-ABC1 antibody, anti-ATP-binding Cassette 1 antibody, anti-ATP-binding Cassette Transporter 1 antibody, anti-CERP antibody, anti-Cholesterol Efflux Regulatory Protein antibody, anti-ABC-1 antibody |
| Immunogen: | Mouse ABCA1-expressing HeLa stable transfectants. |
| Epitope: | Extracellular determinants on ABCA1 of an unknown position. |
| Specificity: | This antibody is specific for ABCA1. |
| Purity: | Whole antisera |
| Packaging: | 0.1 ml Whole antisera Rat ascites. |
| Package Size: | 0.1 ml |
| Concentration: | 29 mg/ml |
| Uses: | NB 400-165 may be used for Flow Cytometry. NB 400-165 is not reactive in Western Blot or ELISA. Suggested working dilutions: * FACS - 1:1,000-1:30,000 *The investigator should determine the optimal working dilution for a specific application. |
| Application Summary: | WB, ELISA, FACS |
| General References: | 1. Trompier, D and Chimini, G. ABCA1, Alliance for Cellular Signaling and Nature Publishing Group, Molecular pages. doi: 10.1038/mp.a002593.01 [website: http://www.signaling-gateway.org/molecule/](2005)2. Oram, JF and Heinecke, JW. Physiol Rev. 85:1343- |