| Catalog Code: | NB400-132 |
| Product Type: | Primary Antibody |
| Product Name: | ABCG1 Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 9619 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-ABCG1 |
| Cross Reactivity: | This antibody reacts with mouse and human protein. Other species have not been tested. There is 100%/100% identity/homology of the immunogen used for this production and the human protein sequence. There is 84%/89% for mouse and 78%/88% for rat. |
| Species Summary: | Hu, Mu |
| Background: | ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-lade |
| Alternate Names: | anti-ABC8 antibody, anti-MGC34313 antibody, anti-WHITE1 antibody |
| Immunogen: | A synthetic peptide made to an internal region of human ABCG1 (between residues 300-400). |
| Specificity: | The specificity of this antibody is for ABCG1. |
| Purity: | peptide affinity purified |
| Packaging: | 0.1 ml peptide affinity purified Rabbit antisera. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | This antibody is useful for Western blot on mouse peritoneal macrophages treated with 22-R-hydroxycholesterol and T0901317 (stimulating ABCG1 expression) and immunohistochemistry. The theoretical molecular weight of ABCG1 is ~75.6 kDa, as seen by Western |
| Application Summary: | IHC, WB |
| Product References: | 1. Avallone, R., Demers, A., Rodrigue-Way, A., Bujold, K., Harb, D., Anghel, S., Wahli, W., Marleau, S., Ong, H., and Tremblay, A. (2006) A Growth Hormone-Releasing Peptide that Binds Scavenger Receptor CD36 and Ghrelin Receptor Up-Regulates Sterol Transp |
| Novus References: | 1. Tansley, Gavin H., et al. "The Cholesterol Transporter ABCG1 Modulates The Subcellular Distribution and Protecolytic Processing of B-Amyloid Precursor Protein." Journal of Lipid Research. doi: 10.1194/jlr.M600542-JLR200, 2007. 2. Wang, M., et |
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