| Catalog Code: | NB400-110 |
| Product Type: | Primary Antibody |
| Product Name: | ABCG8 Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 64241 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-ABCG8 |
| Cross Reactivity: | Human. Does not appear to cross react with mouse. |
| Species Summary: | Hu, Mu(-) |
| Background: | ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorpti |
| Alternate Names: | anti-ATP binding cassette sub family G (WHITE) member 8 (sterolin 2) antibody, anti-ATP binding cassette sub family G member 8 antibody, anti-MGC142217 antibody, anti-Sterolin 2 antibody, anti-STSL antibody, anti-ATP binding cassette G8 antibody |
| Immunogen: | A synthetic peptide from the N-terminal region of human ABCG8 protein. |
| Specificity: | Specific for ABCG8. |
| Purity: | Immunogen affinity purified |
| Buffer: | PBS |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | This antibody can be used for Western blot at 1:500 dilution (ECL). It does not appear to be applicable in immunohistochemistry. |
| Application Summary: | WB |
| General References: | 1.Patel, S.B., et al. Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8,respectively. Am. J. Hum. Genet., 69: 278-290. 2001 2.Garcia, C. |
| Novus References: | 1. Kobayashi, A., et al. Efflux of sphingomyelin cholesterol and phosphatidylcholine by ABCG1. J. Lipid Res. 47:1791-1802, 2006.2. Mathur, S. N., Watt, K. R., and Field, F. J. (2007) Regulation of intestinal NPC1L1 expression by dietary fish oil and docos |