| CatalogCode: | NB300-869 |
| ProductName: | AKAP6 Antibody |
| Product Description: | Goat Polyclonal anti-AKAP6 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide LTMSVTLSPLRSQ-C, representing the N-Terminus of the human protein according to NP_004265. |
| CrossReactivity: | Tested: Expected from sequence similarity: Human, Rat, Mouse |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, preliminary experiments gave no signal but low background in Human Brain and Heart extracts. However this used our routine western blotting protocol which we would not expect to reliably detect proteins as large as the predicted size of approx. 267KDa according to NP_004265. Not tested in other applications.Recommended Starting Dilution:*ELISA (peptide): 1:16,000WB: 1ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognize native protein in any application. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| ListPrice: | 195 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-AKAP6 antibody, anti-ADAP6 antibody, anti-PRKA6 antibody, anti-mAKAP antibody, anti-ADAP100 antibody, anti-AKAP100 antibody, anti-KIAA0311 antibody, anti-A kinase (PRKA) anchor protein 6 antibody, anti-A-kinase anchor protein 100 antibody |
| ProteinTarget: | AKAP6 |
| PackageSize: | 0.1 mg |
| GeneralRef: | McCartney S, Little BM, Langeberg LK, Scott JD. Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum. J Biol Chem. 1995 Apr 21;270(16):9327-33. PMID: 7721854 |
| NotesMain: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application. |
| Gene_Id: | 9472 |
| Omim_ID: | H00009465-M01 |
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