| Catalog Code: | NB300-724 |
| Product Type: | Primary Antibody |
| Product Name: | NOS Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 4842 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-NOS |
| Cross Reactivity: | Cross-reacts with Human, Rat, Mouse and Dog. Expected to cross-react with Cow due to sequence homology. Not yet tested in other species. |
| Species Summary: | Hu, Rt, Mu, Ca |
| Background: | Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of th |
| Immunogen: | Synthetic peptide: PYNSSPRPEQHKSYK-C, corresponding to amino acids 599-613 of Cow eNOS. |
| Specificity: | This antibody detects eNOS. It does not detect brain NOS (bNOS) or inducible NOS (iNOS). |
| Purity: | Whole antisera |
| Buffer: | PBS with 0.05% sodium azide |
| Packaging: | 100 microlitres Liquid. |
| Package Size: | 0.1 ml |
| Uses: | Immunocytochemistry: use at a dilution of 1/250. Western Blot: use at a dilution of 1/1000. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user.By Western blot, this antibody detects an approximately 1 |
| Application Summary: | ICC, WB |
| General References: | Zhao W et al. Experimental allergic encephalomyelitis in the rat is inhibited by aminoguanidine, an inhibitor of nitric oxide synthase. J Neuroimmunol 64:123-33 (1996). Stefanovic-Racic M et al. Nitric oxide and arthritis. Arthritis Rheum |
| Product References: | Sladek SM et al. Granulated metrial gland cells contain nitric oxide synthases during pregnancy in the rat. Placenta 19:55-65 (1998). Dimmeler S et al. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting |