| CatalogCode: | NB300-695 |
| ProductName: | Prostaglandin E Receptor EP3 Antibody |
| Product Description: | Rabbit Polyclonal anti-Prostaglandin E Receptor EP3 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide. |
| CrossReactivity: | Cross-reacts with Human, Mouse and Rat. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | IHC: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: 1/500. Detects a band of approximately 55 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Integral membrane protein. Cell Membrane, Nuclear membrane and Plasma membrane |
| Background: | Prostaglandin E Receptor EP3 is a member of the G protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Prostaglandin E2 Receptor EP3 expression has been documented throughout the periphery, especially kidney. ESTs have been isolated primarily from kidney libraries. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Preservative: 0.02% Sodium Azide |
| ListPrice: | 325 |
| AppSummary: | IHC, IP, WB |
| SpeciesSummary: | Hu, Mu, Rt |
| ALTnames: | anti-EP 3 antibody, anti-EP3 antibody, anti-EP3 I antibody, anti-EP3 II antibody, anti-EP3 III antibody, anti-EP3 IV antibody, anti-EP3e antibody, anti-HGNC:9595 antibody, anti-MGC141828 antibody, anti-MGC141829 antibody, anti-MGC27302 antibody, anti-PGE receptor EP3 subtype antibody, anti-PGE2 R antibody, anti-PGE2R antibody, anti-Prostaglandin E receptor 3 (subtype EP3) antibody, anti-Prostaglandin E receptor 3 antibody, anti-Prostaglandin E2 receptor antibody, anti-Prostaglandin E2 receptor EP3 subtype antibody, anti-Prostaglandin receptor (PGE 2) antibody, anti-Prostanoid EP3 receptor antibody, anti-PTGER 3 antibody, anti-PTGER3 antibody |
| ProteinTarget: | Prostaglandin E Receptor EP3 antibody |
| PackageSize: | 0.1 mg |
| GeneralRef: | This product has been used in:Morath R et al. Immunolocalization of the four prostaglandin E2 receptor proteins EP1, EP2, EP3, and EP4 in human kidney. J Am Soc Nephrol 10:1851-60 (1999). Kotani M et al. Molecular cloning and expression of multiple isoforms of human prostaglandin E receptor EP3 subtype generated by alternative messenger RNA splicing: multiple second messenger systems and tissue-specific distributions. Mol Pharmacol 48:869-79 (1995). Farooqui SM et al. Antibodies against synthetic peptides predicted from the nucleotide sequence of D2 receptor recognize native dopamine receptor protein in rat striatum. J Neurochem 57:1363-9 (1991). |
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